Perioperative Health

Modern surgery optimized the procedure. We optimize the patient.

Prepare. Recover.

PERIOME is a perioperative health company founded by board-certified anesthesiologists. We exist to close the gap between surgical excellence and patient physiologic readiness — before the procedure begins and through the recovery that follows.

Built by Anesthesiologists Clinically Formulated Institutionally Built

Athletes prepare for competition. Astronauts prepare for launch. Patients don't prepare for surgery.

Surgical technique has never been more precise. The facility, the team, the instruments — all optimized, credentialed, and measured. The physiologic condition a patient brings to the OR — metabolic state, mitochondrial reserve, inflammatory baseline, hydration — has no equivalent standard. That is the gap PERIOME was built to close.

50M+
Surgical procedures in
the U.S. annually
0
Widely adopted patient
preparation standards
4th
Pillar of surgical care —
the patient's own physiology

From the Founder

Dr. Chad R. Greene, D.O.

Board-Certified Anesthesiologist
Founder & CEO, PERIOME

"We optimize the surgeon, the anesthesia, and the facility. We do not optimize the patient. Every day I work in the OR, I watch people enter one of the most physiologically demanding events of their lives with no structured preparation. That's the gap. That's what PERIOME is building."

The Fourth Pillar

Modern surgery has three pillars. It needs a fourth.

The surgeon. The anesthesiologist. The facility. Each is optimized and systematically managed. The patient's physiologic condition entering surgery has no structured standard and no clear owner. PERIOME is building the infrastructure for the fourth pillar.

01
The Surgeon
Surgical technique & operative precision
02
The Anesthesiologist
Intraoperative pharmacologic management
03
The Facility
Systems, environment & perioperative infrastructure
04
Patient Physiologic Readiness
Perioperative health optimization — PERIOME.

The Protocol

From scheduling to recovery. One continuous standard.

Designed to integrate at the point of surgical scheduling — fitting inside the workflows your team already runs.

01
Surgery Scheduled
PERIOME PROTOCOL is initiated at the point of scheduling — not the morning of surgery. Preparation begins when it can still make a physiologic difference.
02
7-Day Preparation
One daily stick pack for seven days prior to surgery. Structured physiologic support during the window when conditioning is most achievable.
03
Day of Surgery
The patient arrives with structured physiologic preparation in place — not just instructions on what to avoid, but active conditioning for what the body is about to face.
04
7-Day Recovery
Continued protocol support through the acute recovery window. The physiologic demands of surgery don't end in the OR. Neither does PERIOME.

The Perioperative Genome

Five domains of perioperative physiology. One protocol.

PERIOME PROTOCOL was built domain-by-domain from the physiology of surgical stress — not adapted from a general wellness product. Each domain reflects a distinct physiologic challenge of the surgical window, addressed through a literature-grounded, perioperative-specific rationale.

Review the clinical rationale
Mitochondrial & Metabolic Readiness
Cellular energy support during the fasting window and surgical stress — when metabolic demand is highest and substrate availability is most constrained.
Recovery Physiology
Targeted support for the body's post-operative recovery arc — the physiologic trajectory that determines how a patient moves through the first seven days after surgery.
Neurocognitive Preparation
Support for cognitive baseline entering the OR and clarity through post-anesthetic emergence — a dimension of perioperative experience that standard pre-op instructions do not address.
Hydration & Electrolyte Preparation
Structured oral electrolyte support in the days before surgery — a preparation variable that IV fluids on the day of the procedure cannot retroactively correct.
GI Integrity & Microbiome Support
Gut barrier and microbiome support through fasting, surgical stress, and the antibiotic window — preserving the absorptive capacity the body depends on during recovery.
PERIOME PROTOCOL

One formulation. The entire surgical window.

Seven days before surgery. Seven days after. A single daily stick pack designed to support five distinct physiologic domains across the perioperative period. Developed by an anesthesiologist. Built for the demands of real patients.

14 Day protocol
5 Physiologic domains
1 Daily dose

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always follow your surgical team's instructions.